Archives of physiology and biochemistry

How Different Types of Exercise Affect Muscle TFEB Protein Movement Between Cell Nucleus and Cytoplasm

Updated

Abstract

The transport and modification of the TFEB protein in skeletal muscle are key to regulating the autophagy lysosome system and mitochondrial function.

  • Nuclear cytoplasmic transport and post-transcriptional modification of TFEB are critical processes in skeletal muscle.
  • These processes may influence the regulation of the autophagy lysosome system.
  • TFEB protein is associated with mitochondrial function in skeletal muscle.
  • Responses of these mechanisms to different motor activities remain unclear.

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