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Abstract
Atrial fibrillation (AF) is strongly associated with stroke, heart failure, and mortality.
- Aging is a significant risk factor for the progression of AF.
- Protein lysine acylation is linked to metabolic processes and signaling pathways in AF.
- Acetylation, propionylation, and other acylation types may regulate ion channel activity and mitochondrial function.
- These modifications are associated with oxidative stress, inflammation, and fibroblast activation.
- Understanding these mechanisms could aid in identifying biomarkers and therapeutic targets for AF.
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