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Pro-longevity compounds extend Caenorhabditis elegans male lifespan and reproductive healthspan
Pro-longevity compounds extend lifespan and reproductive health in male Caenorhabditis elegans
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Abstract
All tested conditions extended lifespan in C. elegans males, with seven compounds evaluated.
- Reproductive healthspan, indicated by mating success in late life, improved only with sulforaphane and metformin.
- Findings suggest that lifespan and healthspan can be decoupled in male C. elegans.
- The study provides a framework for evaluating pro-longevity compounds and investigating sex differences in aging.
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