Journal of psychopharmacology (Oxford, England)

Psilocybin lowers fear memories and boosts brain flexibility in memory and thinking areas

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Abstract

Psilocybin may reduce fear memory through its potential effects on neuroplasticity.

  • Posttraumatic stress disorder (PTSD) and major depressive disorder frequently occur together.
  • Psilocybin is believed to have therapeutic effects on depression.
  • Neuroplasticity dysregulation in the hippocampus and medial prefrontal cortex (mPFC) is linked to PTSD.
  • The hypothesis suggests that psilocybin could enhance neuroplasticity in these brain regions.

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