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Psilocybin changes how the brain processes visual context
Updated
Abstract
Essence
Psilocybin may alter perception by changing how visual context shapes judgments and cortical responses.
Evidence
A psychophysics, ultra-high-field fMRI, and computational modeling study tested perception and contextual modulation of cortical responses to visual stimuli.
Caveat
Because the abstract centers on visual tasks and omits sample size and broader behavioral outcomes, the proposed general psychedelic mechanism remains tentative.
Simplified
Key numbers
39%
Increase in (5 mg)
Percent increase in illusion strength compared to placebo.
59%
Increase in (10 mg)
Percent increase in illusion strength compared to placebo.
not quantified
Reduction in
Observed in early visual areas () with psilocybin.
Psychedelic Science