A journey with psychedelic mushrooms: From historical relevance to biology, cultivation, medicinal uses, biotechnology, and beyond

Sep 2, 2023Biotechnology advances

Psychedelic mushrooms: Their history, biology, growing methods, medical uses, and biotechnology

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Abstract

Psychedelic mushrooms containing psilocybin may have therapeutic potential for treating neurological and psychiatric disorders.

  • Traditional uses of psychedelic mushrooms are discussed alongside emerging research trends.
  • Knowledge gaps exist in the diversity and distribution of psilocybin-containing mushrooms.
  • Technologies for quantifying tryptamines and related metabolites are outlined.
  • Current understanding of how psilocybin and related compounds are metabolized in humans is summarized.
  • Both beneficial and hazardous health implications of psilocybin use are identified.
  • Opportunities for using biotechnology and machine learning to modify metabolite profiles are explored.

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