Psychedelics, spirituality, and existential distress in patients at the end of life

Apr 1, 2025Cleveland Clinic journal of medicine

Psychedelics, spiritual feelings, and distress about existence in patients nearing the end of life

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Abstract

Psychedelic-assisted therapy is increasingly recognized for its potential to address spiritual and existential distress at the end of life.

  • Psychedelics may play a role in alleviating nonphysical suffering, specifically spiritual and existential distress.
  • Clinical trials over the last decade have highlighted the therapeutic potential of psychedelics in end-of-life care.
  • The discussion encompasses medical, ethical, and legal perspectives related to the use of psychedelics in therapy.
  • There is a growing interest in further research to explore the implications of psychedelics for treating such distress.

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Full Text

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