World journal of clinical pediatrics

Probiotics for Children with Autism: Review of Benefits, How They Work, and Use in Treatment

Updated

Abstract

Autism spectrum disorder (ASD) is frequently associated with gastrointestinal disturbances and changes in gut microbiota composition.

  • Emerging evidence suggests a connection between gut health and the brain in individuals with ASD.
  • The microbiota-gut-brain axis may influence the development and symptoms of ASD.
  • Interest is growing in therapies targeting the gut microbiome, such as probiotics, prebiotics, synbiotics, and fecal microbiota transplantation.
  • Clinical effectiveness and underlying mechanisms of these microbiome-targeted therapies are not fully understood.
  • Variability in study designs and outcomes complicates the assessment of these interventions.

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