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Abstract
Dysregulation of the brain-gut-microbiome axis is implicated in both gastrointestinal diseases and neuropsychiatric disorders.
- The brain-gut axis involves communication between the central nervous system and the enteric nervous system through various pathways.
- Alterations in the gut microbiome may contribute to disorders such as irritable bowel syndrome, depression, Alzheimer's disease, and autism spectrum disorder.
- Changes in the gut microbiome are associated with the development of organic gastrointestinal diseases, including inflammatory bowel disease.
- Prebiotics, probiotics, or postbiotics could offer new treatment options by modifying the gut microbiome or mimicking gut microbial signals.
- Despite advances in understanding the brain-gut-microbiome axis, clinical data to support these findings is currently lacking.
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