Psychosocial interventions and medication adherence in bipolar disorder

Aug 12, 2008Dialogues in clinical neuroscience

How Social Support and Therapy Affect Taking Medication in Bipolar Disorder

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Abstract

Psychosocial interventions may reduce psychosocial disability associated with bipolar disorder.

  • Randomized controlled trials show improvements in symptoms, psychosocial functioning, and treatment adherence.
  • Standardized treatment manuals guide various psychosocial interventions with differing formats and durations.
  • Cognitive-behavioral therapy, family-focused therapy, interpersonal and social rhythms therapy, and psychoeducation have the most empirical support.
  • Enhancing adherence to pharmacotherapy is crucial due to its association with relapse, hospitalization, and health care costs.
  • Complex nonadherence behaviors often necessitate multicomponent interventions.

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Key numbers

40%
Nonadherence Rate
Estimated prevalence of nonadherence among individuals with bipolar disorder.
7 of 11
Effectiveness of Interventions
Number of clinical trials demonstrating positive effects on adherence out of those reviewed.

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