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Abstract
Obese rats were used to investigate the effects of the GLP-1 receptor agonist semaglutide and the NPY 2 receptor agonist PYY3-36 on liver mitochondria.
- The study examined mitochondrial oxygen consumption in liver cells.
- Reactive oxygen species (ROS) emission from liver mitochondria was measured.
- Incretins may have distinct impacts on mitochondrial function in the context of metabolic liver disease.
- The mechanisms by which incretins affect liver metabolism remain unclear.
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