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Quercetin and Derivatives Ameliorate Metabolic Disturbances by Regulating Gut Metabolite Profiles in Mice with Circadian Rhythm Disruption and High-Fat Diet
Quercetin and related compounds improve metabolism by changing gut metabolites in mice with disrupted body clocks and high-fat diets
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Abstract
Quercetin and its derivatives significantly alter the intestinal metabolite profile in mice.
- Metabolic abnormalities were induced in mice through circadian rhythm disruption and a high-fat diet.
- Quercetin and its derivatives showed potential in alleviating these metabolic disturbances.
- A non-targeted fecal metabolomics analysis was conducted to evaluate the effects of quercetin.
- These changes in metabolite profiles may provide insights for developing quercetin-based functional foods.
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