Biochimica et biophysica acta. Molecular basis of disease

Rapamycin may reduce age-related changes and irregular heartbeat in the heart by improving metabolism controlled by HIF-1α

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Abstract

Rapamycin is recognized for its potential to extend lifespan.

  • Atrial fibrillation (AF) is linked to aging and poses significant health risks.
  • The effects of rapamycin on age-related changes in heart tissue and AF risk are not well understood.
  • Understanding how rapamycin influences atrial remodeling could help address AF susceptibility.

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