Vaccine

Real-world safety and effectiveness of protein-based and mRNA COVID-19 vaccines

Updated

Abstract

Real-world data on vaccine effectiveness (VE) and relative VE (rVE) for the 2023-2024 COVID-19 vaccines is crucial for policy recommendations.

  • The effectiveness of protein-based and mRNA COVID-19 vaccines against symptomatic SARS-CoV-2 infections may influence public confidence.
  • Safety assessments of the 2023-2024 vaccines are being conducted to ensure their suitability for widespread use.
  • Evaluating the VE and rVE helps inform health policies related to COVID-19 vaccination strategies.

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Full Text

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Funding

Competing interests

Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Dr. Yoon has received funding from Novavax, Inc. pertaining to this study and the Centers for Disease Control and Prevention (CDC) for prior COVID-19 vaccine studies and has served as an advisory board member for Pfizer–BioNTech, but without compensation for that role. Dr. Phillips, Dr. Ellsworth, Ms. Chen, Ms. Yan Dr. Zhao have received institutional grant funding from Novavax, Inc. Dr. Battan-Wraith, Dr. Rowley, Dr. Ball, and Dr. Yates, and Ms. Fink were funded through contract agreement with the University of Utah with prime funding and study drug provided by Novavax, Inc. They are employees of Westat, Inc., which has received funding from CDC for vaccine effectiveness studies. Dr. Thiese has received funding from the American College of Occupational and Environmental Medicine and the National Institute for Occupational Safety and Health, outside this work. Dr. Toback and Dr. Rousculp are employees of Novavax, Inc. and may hold Novavax, Inc. stock. Dr. Zhang does not have anything to disclose. Dr. Dunkle is a former employee of Novavax, Inc. and may hold Novavax, Inc. stock.
PubMed

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