Regenerative therapyNov 16, 2022

New treatments to help hair grow and regrow: a summary of research

Regenerative Health Weekly Brief ↗PubMed ↗DOI ↗

Updated Mar 14, 2026

Abstract

Mesenchymal stem cell implantation and platelet-rich plasma therapies are potential treatment options for alopecia.

Alopecia is linked to various psychosocial and medical conditions, contributing to economic burdens.
Conventional medical interventions for alopecia have several limitations.
Regenerative medicine approaches, including MSC implantation and MSC-derived secretome treatment, are being explored as alternatives.
Blood-derived platelet-rich plasma therapies may also provide promising treatment options for hair loss.
A review of literature from multiple databases highlights the potential of these therapies in promoting hair growth.

Simplified

Hair loss, or alopecia, is associated with several psychosocial and medical comorbidities, and it remains an economic burden to individuals and the society. Alopecia is attributable to varied mechanisms and features a multifactorial predisposition, and the available conventional medical interventions have several limitations. Thus, several therapeutic strategies for alopecia in regenerative medicine are currently being explored, with increasing evidence suggesting that mesenchymal stem cell (MSC) implantation, MSC-derived secretome treatment, and blood-derived platelet-rich plasma therapies are potential treatment options. In this review, we searched the Cochrane Library, MEDLINE (PubMed), EMBASE, and Scopus using various combinations of terms, such as "stem cell," "alopecia," "hair loss," "Androgenetic alopecia," "male-pattern hair loss," "female-pattern hair loss," "regenerative hair growth," "cell therapy," "mesenchymal stem cells," "MSC-derived extracellular vesicles," "MSC-derived exosomes," and "platelet-rich plasma" and summarized the most promising regenerative treatments for alopecia. Moreover, further opportunities of improving efficacy and innovative strategies for promoting clinical application were discussed.

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Competing interests

The authors have no conflicts of interest to declare for this work.

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New treatments to help hair grow and regrow: a summary of research

Abstract

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