Regulation of metabolism: the circadian clock dictates the time

Dec 16, 2011Trends in endocrinology and metabolism: TEM

The body’s internal clock controls metabolism timing

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Abstract

Circadian rhythms operate on a cycle of approximately 24 hours and influence various metabolic and physiological functions.

  • Disruption of circadian rhythms is linked to sleep disorders, depression, metabolic syndrome, and cancer.
  • Molecular components of the circadian clock interact with cellular metabolism regulators.
  • Metabolite availability and feeding behavior can influence the regulation of the circadian clock.
  • Understanding the relationship between circadian rhythms and metabolism may inform therapeutic strategies for metabolic disorders.

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