Current obesity reports

How Obesity-Related Cell Signals Change the Immune Environment to Support Tumor Growth

Updated

Abstract

Obesity is a potent risk factor for cancer, primarily driven by chronic inflammation.

  • Chronic inflammation associated with obesity may contribute to the development of cancer.
  • Adipose tissue dysfunction is linked to tumor formation through the induction of cellular aging.
  • The cellular aging process is characterized by the Senescence-Associated Secretory Phenotype (SASP), which is not clearly defined.

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