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Abstract
Over three billion individuals worldwide are affected by aging-related neurological disorders.
- Aging is associated with the increased incidence and progression of neurological disorders through mechanisms such as endothelial dysfunction and oxidative stress.
- Chronic inflammation, mitochondrial dysfunction, cellular senescence, metabolic imbalance, and gut microbiota dysbiosis also contribute to these disorders.
- These processes impair neuronal survival, synaptic plasticity, and cognitive and motor functions.
- Traditional Chinese medicine may offer multi-component strategies that exert neuroprotective, anti-inflammatory, and antioxidant effects.
- Preclinical studies indicate that TCM interventions could modulate autophagy and restore metabolic balance.
- High-quality clinical evidence on the safety and efficacy of TCM for these conditions remains limited.
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