Strength of daily activity-rest patterns and future mood symptoms in teenagers: roles of natural sleep timing, sleep habits, and sensitivity to rewards

Greater reward sensitivity or eveningness may influence the connection between rest-activity rhythm disruption and mood symptoms related to bipolar spectrum disorder.

• Adolescence is a time of increased risk for bipolar spectrum disorder, particularly influenced by changes in reward and circadian systems.
• Circadian disruptions are linked to mood destabilization, especially in individuals with underlying vulnerabilities.
• Rest-activity rhythm disruption could be associated with mood symptoms that are relevant to bipolar spectrum disorder.
• The predictive relationship between reward sensitivity, eveningness, and mood symptoms is being examined.

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