Creation and early testing of resveratrol-like compounds that may affect cell aging proteins and reduce inflammation

Resveratrol is associated with anti-aging and anti-inflammatory effects but has low oral bioavailability.

• Resveratrol may activate sirtuin 1 (SIRT1), which is linked to anti-aging and life extension benefits.
• The compound inhibits cyclooxygenase-2 (COX-2), potentially providing anti-inflammatory effects in conditions like atopic dermatitis and psoriasis.
• Carbostyril derivatives, designed as resveratrol-like compounds, may function as SIRT1 modulators or COX inhibitors.
• The carbostyril scaffold is noted for its biological stability and low toxicity, suggesting potential for safer pharmaceutical applications.

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