InflammopharmacologySep 23, 2025

Resveratrol's possible benefits for eye health

Longevity & Aging Weekly Brief ↗PubMed ↗DOI ↗

Updated Jan 7, 2026

Abstract

Resveratrol may provide a safer, non-invasive alternative for managing age-related ocular diseases associated with oxidative stress and inflammation.

Resveratrol shows significant antioxidant and anti-inflammatory properties.
It has been linked to potential benefits in cardioprotection, chemoprotection, neuroprotection, and anti-aging.
In vitro and animal studies suggest resveratrol impacts biological pathways relevant to ocular diseases, including oxidative stress modulation and inflammation reduction.
The compound may help suppress abnormal blood vessel growth, a factor in various eye conditions.
Research indicates resveratrol could serve as a nutritional intervention for managing diseases like glaucoma and diabetic retinopathy.

Simplified

Resveratrol, a polyphenolic compound predominantly found in grapes and red wine, exhibits significant biological activity due to its potent antioxidant and anti-inflammatory properties. Known for its cardioprotective, chemotherapeutic, neuroprotective, and anti-aging effects, resveratrol has garnered attention for its potential in managing age-related ocular diseases, such as glaucoma, cataract, diabetic retinopathy, and macular degeneration-conditions, where oxidative stress and inflammation play central roles in disease progression and vision impairment. Both in vitro and animal studies indicate that resveratrol impacts key biological pathways, including oxidative stress modulation, inflammation reduction, mitochondrial protection, apoptosis regulation, and angiogenesis suppression, which are implicated in the pathology of these ocular conditions. Resveratrol with antioxidant, anti-inflammatory, and anti-angiogenic properties, shows promise in treating ophthalmic diseases by targeting oxidative stress and abnormal angiogenesis, offering a safer, non-invasive alternative to conventional drugs and better scientific validation than herbal remedies. This review synthesizes current research on resveratrol's mechanisms of action, therapeutic potential, and limitations as a treatment for eye disorders, highlighting its promise as a nutritional intervention and areas requiring further exploration.

Full Text

Full text is available at the source.

View Full Text ↗

Funding

Competing interests

Declarations. Conflict of interest: The author declares that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Peer reviewers on this manuscript have no relevant financial or other relationships to disclose. Ethical approval and informed consent: This review article is based on previously conducted studies and does not involve any human participants or animals, beyond their involvement in the previously published articles we cite. Therefore, no ethical approval and informed consent is required for this study. Publication enhancement: No publication enhancement materials were used. Permissions: No third-party contents were used in our review article. Trial registration: This is a review article; therefore, it does not require any trial registration.

PubMed

Resveratrol's possible benefits for eye health

Abstract

Full Text

Funding

Competing interests

You found one interesting study. We’ll send the next 7.

What Lands in Your Inbox Each Week:

Recent issues from the longevity & aging brief