The Journal of investigative dermatology

The past and future of RNA-based medicines

Updated

Abstract

RNA therapeutics may offer faster and less expensive development compared to traditional drugs.

  • RNA therapeutics utilize various types of RNA to address a wide range of diseases.
  • These therapies include modalities like antisense oligonucleotides, small interfering RNAs, microRNAs, mRNAs, and aptamers.
  • The success of mRNA vaccines for SARS-CoV-2 has spurred interest in RNA approaches for conditions with limited treatment options.
  • Potential applications include chronic wounds, aggressive metastatic melanoma, and autoimmune and genetic skin diseases.

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