Advancements in RNA-targeted therapies for renal cell carcinoma

May 31, 2025European journal of pharmacology

New RNA-based treatments for kidney cancer

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Abstract

Elevated mortality rates in renal cell carcinoma (RCC) are primarily due to resistance to traditional therapies.

  • Recent RNA-targeted therapies may enhance the effectiveness of treatments for RCC.
  • Innovative strategies include antisense oligonucleotides, small interfering RNAs, and CRISPR/Cas9.
  • These therapies are associated with high specificity and effectiveness in preclinical models.
  • There is a focus on personalized medicine to optimize outcomes for RCC patients.
  • Advancements in delivery mechanisms could improve the integration of these therapies with current treatments.

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