Chinese journal of natural medicines

Saponins' possible benefits for brain diseases through the gut-brain connection

Updated

Abstract

Neurological diseases are increasingly linked to dysfunction in the gut-brain axis.

  • The gut-brain axis facilitates interactions between the gastrointestinal tract and the nervous system.
  • Dysfunction in this axis is associated with various neurological diseases.
  • Saponins, found in Traditional Chinese Medicine, may provide neuroprotective effects.
  • Research suggests that saponins could influence key mediators within the gut-brain axis.
  • Targeting the gut-brain axis with saponins is considered a promising approach for neuroprotection.

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