is positively correlated with (β = 0.663, p < 0.001) and negatively correlated with (β = -0.748, p < 0.001).
Sarcopenia may have a negative impact on mental health in older adults.
partially mediate the relationship between sarcopenia and mental health.
The mediating effect of activities of daily living is stronger for depressive symptoms (18.77%) compared to cognitive functions (12.82%).
These findings suggest a complex interaction between physical health and mental well-being in the elderly.
Simplified
BACKGROUND: Most existing studies focus on either the relationship between and or sarcopenia and . Few studies have examined depressive symptoms and cognitive functions simultaneously. This study aimed to analyze the relationship between sarcopenia and both depressive symptoms and cognitive functions in the elderly by introducing to explore the mediating role of activities of daily living between sarcopenia and mental health.
METHODS: This study used data from the 2015 and 2018 China Health and Retirement Longitudinal Study, including a total of 3,552 older adults aged 60 and above. We conducted descriptive statistical analysis and correlation analysis on the data and used seemingly unrelated regression to examine the relationship between sarcopenia, depressive symptoms, and cognitive functions in older adults. Bootstrap mediation analysis was used to further explore the mediating role of activities of daily living in the relationship between sarcopenia and depressive symptoms and cognitive functions in the elderly.
RESULTS: After adjusting for confounding factors, sarcopenia was positively correlated with depressive symptoms (β = 0.663, p < 0.001) and negatively correlated with cognitive functions (β=-0.748, p < 0.001), indicating a negative impact of sarcopenia on mental health. Activities of daily living mediated the relationship between sarcopenia and mental health, with a stronger mediating effect between sarcopenia and depressive symptoms (18.77%, β = 0.125, 95%CI (0.035, 0.222)) than between sarcopenia and cognitive functions (12.82%, β=-0.099, 95%CI (-0.162, -0.035)).
CONCLUSIONS: Activities of daily living partially mediated the relationship between sarcopenia and mental health status in Chinese older adults. Interventions targeting sarcopenia and activities of daily living may be an effective way to prevent and improve the mental health status of older adults.
Key numbers
0.663
Increase in
positively predicts (β = 0.663, p < 0.001).
-0.748
Decrease in
negatively predicts (β = -0.748, p < 0.001).
18.77%
Mediating Effect on
accounts for 18.77% of the total effect on .
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Declarations. Ethics approval and consent to participate: This study adhered to the principles of the Declaration of Helsinki and was reviewed and approved by the Ethical Review Committee of Peking University (IRB00001052-11015). Informed consent was obtained from all participants before their inclusion in the study. Consent for publication: Not applicable. Clinical trial number: Not applicable. Competing interests: The authors declare no competing interests.
