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Relationships between sarcopenia, nutrient intake, and gut microbiota in Chinese community-dwelling older women
Links between muscle loss, diet, and gut bacteria in older Chinese women living in the community
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Abstract
The prevalence of sarcopenia was 19.20% among 276 female participants.
- Sarcopenic patients showed significantly lower intake of dietary protein, fat, fiber, and several vitamins and minerals.
- Richness of gut microbiota, as measured by Chao1 and ACE indexes, was considerably reduced in sarcopenic individuals.
- Specific gut bacteria and their metabolites were decreased in sarcopenic patients, including Firmicutes/Bacteroidetes, Agathobacter, Dorea, and Butyrate, while Shigella and Bacteroides were enriched.
- Agathobacter and Acetate were positively correlated with grip strength and gait speed, while Bifidobacterium was negatively correlated with grip strength and appendicular skeletal muscle index (ASMI).
- Protein intake was positively related to the presence of Bifidobacterium.
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