Aging-related markers predict physical ability and health outcomes after heart failure hospitalization

Acute decompensated heart failure is the most common cause of hospitalization in older adults.

• Cellular senescence may play a role in the development of heart failure.
• The senescence-associated secretory phenotype (SASP) is linked to inflammation and functional decline.
• There is an evaluation of the relationship between SASP and physical function in older adults with heart failure.

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