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Abstract
Sequence-defined polymeric systems may enhance gene delivery efficiency compared to traditional polymers.
- Traditional polymers used for gene delivery often suffer from structural variability and unpredictable performance.
- Sequence-defined polymers allow for precise control over their molecular structure and charge distribution.
- Improved structural precision in polymeric carriers is associated with better functional performance in gene delivery.
- These advancements could facilitate overcoming biological barriers and achieving targeted delivery to specific tissues.
- Various synthetic methods, including solid-phase synthesis and flow chemistry, enable the development of these precise polymers.
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