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Abstract
Psychobiotics may restore neurotransmitter balance by modulating pro-inflammatory cytokines and enhancing brain-derived neurotrophic factor expression.
- Preclinical evidence suggests psychobiotics confer mental health benefits by influencing the gut-brain axis.
- Challenges include a limited number of clinical studies and uncertainty regarding optimal dosages and long-term effects.
- Recent studies indicate psychobiotics may enhance tryptophan metabolism and facilitate serotonin synthesis.
- The specific mechanisms by which bacteria contribute to serotonin biosynthesis remain inadequately understood.
- Exploration of the interplay between psychobiotics and food matrices could address limitations in current therapeutic interventions.
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