Advances in Severe Traumatic Brain Injury Complicated With Intestinal Failure

Patients with severe traumatic brain injury have a high incidence of intestinal failure.

• Intestinal failure in these patients is associated with systemic stress response and gut-brain axis dysfunction.
• Main risk factors include gastrointestinal dysfunction, intestinal barrier injury, and drug effects.
• Clinical assessment tools are available to evaluate the condition of patients with intestinal failure.
• Therapeutic interventions centered on enteral nutrition may improve nutritional status and protect gut mucosal integrity.
• Individualized treatment plans could reduce the incidence of complications in patients with severe traumatic brain injury.

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