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Abstract
Activation of sirtuins may protect skin cells from the effects of photoaging.
- Photoaging and chronological aging are associated with changes in cellular function, including telomere shortening.
- Accumulation of senescent skin cells is a significant factor in the decline of skin integrity and function.
- Sirtuins are identified as key regulators of cellular functioning and homeostasis in skin.
- Targeting sirtuins could offer a potential strategy to mitigate the impacts of aging on skin cells.
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