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Abstract
Sirtuins (SIRT1-7) are implicated in various health conditions, including cancer and aging-related diseases.
- Sirtuins are enzymes that link metabolic status to epigenetic regulation and other cellular processes.
- Dysregulation of sirtuins is associated with several diseases, including cancer, neurodegeneration, and cardiometabolic disorders.
- Sirtuins play roles in maintaining genome integrity, mitochondrial function, and responding to stress.
- These enzymes represent a complex but promising target for drug discovery.
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