Sleep neurology: pearls and pitfalls

📖 Top 30% JournalJan 12, 2026Practical neurology

Key Insights and Challenges in Sleep-Related Brain Disorders

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Abstract

Chronic insomnia affects approximately 10% of adults.

  • Multiple sleep disorders, such as obstructive sleep apnoea and restless legs syndrome, are often under-recognised and misdiagnosed.
  • Cognitive behavioural therapy for insomnia is the recommended first-line treatment, yet access to this therapy is limited.
  • There is a tendency to initiate medications prematurely for sleep disorders, despite the availability of effective non-pharmacological treatments.
  • Emerging therapies, including dual orexin receptor antagonists and orexin-based treatments, could enhance management of insomnia and narcolepsy but need careful implementation.
  • Improper use of medications, especially dopamine agonists for restless legs syndrome, may lead to worse health outcomes.

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