How Sleep Quality, Body Clock Problems, and Daily Function Relate to Treatment Sticking in Major Depression

Sleep disturbances and circadian rhythm disruption are prevalent in major depressive disorder (MDD).

• Sleep quality is linked to biological rhythm disruption in patients with MDD.
• Functional status may be affected by the quality of sleep in this population.
• Medication adherence is potentially associated with sleep disturbances and circadian rhythm issues.
• The study highlights the need for a comprehensive approach to understanding these interrelated factors in outpatient depression.

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