American journal of surgery

Comparing weight loss surgery and hormone-based treatment to improve kidney transplant chances in patients with advanced kidney failure and obesity

Updated

Abstract

14.74% of patients undergoing sleeve gastrectomy received a kidney transplant within 5 years, the highest among the evaluated interventions.

  • Sleeve gastrectomy led to more rapid weight loss, with 27.49% of patients achieving a BMI ≤35 kg/m² by 6 months.
  • The predicted transplant rates at 5 years were 9.06% for dual GLP-1/GIP receptor agonist patients and 4.83% for GLP-1 receptor agonist patients.
  • Sleeve gastrectomy is associated with a survival advantage, especially in patients with higher pre-intervention BMIs.
  • Dual GLP-1/GIP receptor agonist treatment resulted in a significant number of patients undergoing transplantation, indicating its potential as an effective alternative.

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Funding

Competing interests

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
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