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Abstract
Each standard deviation increase in social jet lag was associated with a 5% increase in composite cardiovascular disease risk.
- Social jet lag is defined as the difference in mid-sleep timing between weekdays and weekends.
- Individuals with at least 2 hours of social jet lag had a 30% higher risk of cardiovascular disease.
- The strongest associations were observed for myocardial infarction, ischemic heart disease, and heart failure.
- Severe social jet lag was linked to increased cardiovascular disease risk even in those with normal sleep duration.
- The relationship between social jet lag and cardiovascular disease persisted after considering genetic risk factors.
Simplified
Circadian Biology