Life sciencesAug 27, 2026

Genetic differences in kidney cells linked to kidney disease progression, cell damage, aging, and treatment options

Longevity & Aging Weekly Brief ↗PubMed ↗DOI ↗

Updated Aug 29, 2026

Abstract

Somatic genomic mosaicism may contribute to chronic kidney disease (CKD) progression.

The study aims to evaluate the role of somatic genomic mosaicism in CKD.
Evidence will be graded by strength to assess its contribution to disease progression.
Mosaicism within kidney tissue will be differentiated from clonal changes in blood.

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