SSRI use during early COVID-19 and the risk of Long COVID symptoms in people with depression

Low serotonin may play a role in the long-term effects of COVID-19.

• Long COVID is characterized by a wide range of symptoms affecting various biological systems.
• The diversity of Long COVID symptoms complicates the identification of specific mechanisms involved.
• Selective serotonin reuptake inhibitors (SSRIs) may have the potential to prevent long-term effects associated with COVID-19.
• Examining the relationship between SSRIs and specific Long COVID symptoms could reveal underlying mechanisms.

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