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Stem cell theory: A new horizon for the treatment of endometriosis by targeting mesenchymal stem cell
Using stem cells to develop new treatments for endometriosis
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Abstract
Endometriosis is a prevalent chronic gynecological disease that can involve complex lesions and a tendency for recurrence.
- The stem cell theory suggests that endometrial stem cells and those from outside the uterus may be involved in the formation of endometriosis.
- Terminal cells in ectopic lesions are proposed to be unable to support the long-term development of endometriosis.
- Mesenchymal stem cells (MSCs) are thought to play a role in the progression and potential malignant transformation of endometriosis.
- Recent advancements have enhanced the understanding of MSCs from various sources in the pathogenesis of endometriosis.
- Intervention strategies targeting MSCs are proposed as potential treatments for endometriosis.
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