Obstetrics and gynecology

Steroid Levels in Uterine Muscle and Maternal and Umbilical Blood Before and During Labor

Updated

Abstract

Advanced labor is characterized by a high concentration of estrone in the maternal peripheral vein, umbilical cord, and myometrium.

  • Concentrations of estrone and estradiol in the myometrium increased more significantly than progesterone from the second trimester to term pregnancy.
  • During labor, umbilical cord concentrations of estradiol, progesterone, and cortisol also rose.
  • There were no significant changes in myometrial concentrations of estrone, estradiol, or progesterone during labor.
  • In term pregnancies, the myometrial concentration of estrone was found to be higher than that of estradiol.

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