Steroids in human myometrium and maternal and umbilical cord plasma before and during labor.

May 1, 1979Obstetrics and gynecology

Steroid Levels in Uterine Muscle and Maternal and Umbilical Blood Before and During Labor

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Abstract

Advanced labor is characterized by a high concentration of estrone in the maternal peripheral vein, umbilical cord, and myometrium.

  • Concentrations of estrone and estradiol in the myometrium increased more significantly than progesterone from the second trimester to term pregnancy.
  • During labor, umbilical cord concentrations of estradiol, progesterone, and cortisol also rose.
  • There were no significant changes in myometrial concentrations of estrone, estradiol, or progesterone during labor.
  • In term pregnancies, the myometrial concentration of estrone was found to be higher than that of estradiol.

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