Suvorexant for the treatment of sleep disorders in children with severe cerebral palsy

Sep 23, 2025Sleep & breathing = Schlaf & Atmung

Suvorexant for treating sleep problems in children with severe cerebral palsy

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Abstract

Suvorexant was effective in 81% of patients with sleep disorders among children with severe cerebral palsy.

  • Sixteen patients aged 2-16 with sleep disorders were treated with suvorexant.
  • Efficacy rates varied by sleep disturbance type, with 100% effectiveness for early awakening disorders.
  • The mean maintenance dose in effective cases was 0.3 mg/kg.
  • Significant reductions in insomnia scores were observed, decreasing from a mean of 15.0 to 4.7.
  • No major adverse events were reported during the study.

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