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Combined and varied aging patterns across multiple body systems using linked aging measures
Updated
Abstract
Essence
Organ-specific biological aging clocks showed heterogeneous aging patterns and stronger links to cardiovascular event risk than chronological age.
Evidence
Observational imaging and multi-phenotype study of 904 adults aged 55-65 from the Taizhou Imaging Study built organ, cognition, and whole-body aging clocks from brain imaging, cognition, blood biochemistry, omics, and physical measures.
Caveat
The study is observational and age-restricted, so mediation and risk associations do not prove that organ aging causes sensory decline or cardiovascular events.
Simplified
Key numbers
12.46%
Brain Aging Mediation
Percentage of mediation effect in the relationship between smoking and olfactory decline.
6.94%
Kidney Aging Mediation
Percentage of mediation effect in the relationship between smoking and olfactory decline.
904 individuals
Study Cohort Size
Total number of participants in the Taizhou Imaging Study.
Longevity & Aging