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Abstract
A polypeptide-based eye drop significantly improved corneal permeability and reduced oxidative stress in models of dry eye disease.
- The treatment combines quercetin and superoxide dismutase in a nanocarrier to enhance therapeutic efficacy.
- Quercetin functions as an anti-aging agent and aids in the effective delivery of superoxide dismutase.
- The eye drop formulation showed improved outcomes compared to free superoxide dismutase.
- Treatment led to restored lacrimal gland function and reversal of key symptoms associated with dry eye disease.
- It effectively reduced activity associated with age-related cellular senescence in dry eye disease models.
Simplified
Longevity & Aging