Synthesis, characterization and biological activities of some new benzo[b]thiophene derivatives

Dec 1, 2009European journal of medicinal chemistry

Creation, analysis, and biological effects of new benzo[b]thiophene compounds

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Abstract

New benzo[b]thiophene derivatives were synthesized and evaluated for their biological activity.

  • Benzo[b]thiophene derivatives may exhibit a wide spectrum of pharmacological properties.
  • The synthesis involved starting from 3-chlorobenzo[b]thiophene-2-carboxyl chloride.
  • Characterization of the compounds was performed using elemental analyses, I.R, NMR, and Mass spectral studies.
  • Selected compounds were screened for antibacterial, antifungal, and anti-inflammatory activities.
  • Many of the synthesized molecules were found to be potent in biological testing.

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Full Text

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