Making and studying different indole β-carboline compounds with various biological effects: a review

Indole β-carboline compounds are associated with multiple pharmacological effects including anticancer and antibacterial activities.

• These compounds have shown various pharmacological effects such as anti-acetylcholinesterase, anti-inflammation, antimalarial, anti-diabetic, and antioxidant activities.
• A significant number of studies on the synthesis and biological activity of indole β-carboline compounds have been conducted over the past 20 years.
• No comprehensive data summary of these studies has been presented until now.
• The review highlights the synthesis pathways and bioactivity of substituted indole β-carboline compounds reported since 2005.

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