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A Case Report of Systemic Allergic Reaction to the Dual Glucose-Dependent Insulinotropic Polypeptide/Glucagon-Like Peptide-1 Receptor Agonist Tirzepatide
A case of a whole-body allergic reaction to the diabetes drug tirzepatide
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Abstract
A 67-year-old woman experienced severe allergic reactions after her first dose of tirzepatide, leading to symptoms such as pruritus and urticaria.
- Severe disseminated itching and a widespread rash occurred following the initial administration of tirzepatide.
- The allergic reaction was alleviated with antihistamines, suggesting a hypersensitivity response.
- The case may indicate the potential for immunoglobulin E-mediated hypersensitivity to tirzepatide.
- Increased awareness is necessary regarding allergic reactions to new diabetes medications, especially GIP/GLP-1 receptor agonists.
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