We can’t show the full text here under this license.
Abstract
-based drug delivery systems may enhance treatment outcomes for .
- Ischemic stroke is associated with high mortality and disability rates globally.
- Limited efficacy of current therapeutic agents poses a challenge in treating ischemic stroke.
- Nanoparticles have unique properties that allow them to cross the blood-brain barrier.
- Pathophysiological mechanisms involved in ischemic stroke include oxidative stress, glutamate excitotoxicity, neuroinflammation, and cell death.
- The classification of nanoparticle-based drug delivery systems according to these mechanisms aids in targeting specific physiological pathways.
- The review discusses potential benefits and challenges of using nanoparticles in ischemic stroke treatment.
Simplified