Targeting the gut microbiota as treatment for obesity and cancer cachexia

The gut microbiota may serve as a novel therapeutic target for addressing metabolic disorders like obesity and cancer cachexia.

• Obesity and cancer cachexia are linked by disrupted energy balance, inflammation, and neuroendocrine dysfunction.
• Both conditions are associated with increased morbidity and mortality.
• Gut microbial metabolites influence metabolic processes through specific signaling pathways.
• Current treatments for obesity and cachexia often do not effectively target the underlying mechanisms.
• Early interventions targeting the gut microbiome show promise but require further investigation to establish effective therapies.

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