From telomeres and senescence to integrated longevity medicine: redefining the path to extended healthspan

May 5, 2025Biogerontology

From Cell Aging and Damage to Combined Treatments: Rethinking How to Extend Healthy Life

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Abstract

Aging is influenced by factors such as oxidative stress, lifestyle choices, and metabolic regulation.

  • Telomere dynamics can be affected by external factors rather than being fixed.
  • Cellular senescence, telomere shortening, and systemic inflammation are key aspects of biological aging.
  • Personalized longevity medicine may utilize telomere-based biomarkers and metabolic interventions.
  • Integrating geroscience into clinical practice could redefine aging as a modifiable process.
  • Strategies focusing on biomarker tracking and preventive interventions may help extend both lifespan and healthspan.

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