Thermoregulation in Sleep Disorders—Comprehensive Review

May 4, 2026Journal of clinical medicine

Body Temperature Control in Sleep Disorders

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Abstract

Disrupted core body temperature (CBT) minima may prolong sleep latency and lead to daytime symptoms.

  • Thermoregulatory processes, including CBT modulation, the distal-proximal temperature gradient (DPG), and melatonin rhythms, play a significant role in sleep regulation.
  • Delayed or disrupted CBT minima and impaired DPG are associated with fragmented sleep.
  • Altered melatonin secretion could contribute to sleep disorders such as insomnia and narcolepsy.
  • Temperature-based interventions, like foot baths and adjustments in room temperature, may help improve sleep quality.
  • Personalized interventions addressing thermoregulatory disruptions could offer noninvasive options for managing sleep disorders.

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